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1

BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

Bouillet, Philippe, Purton, Jared F., Godfrey, Dale I., Zhang, Li-Chen, Coultas, Leigh, Puthalakath, Hamsa, Pellegrini, Marc, Cory, Suzanne, Adams, Jerry M., Strasser, Andreas

Journal:

Year:

2002

Language:

english

File:

PDF, 591 KB

english, 2002

2

[Methods in Molecular Biology] Programmed Cell Death Volume 1419 ||

Puthalakath, Hamsa, Hawkins, Christine J.

Year:

2016

Language:

english

File:

PDF, 9.78 MB

english, 2016

3

Genetic defect in N-acetylglucosaminyltransferase I gene of a ricin-resistant baby hamster kidney mutant

OPAT, Andrew S., PUTHALAKATH, Hamsa, BURKE, Jo, GLEESON, Paul A.

Journal:

Biochemical Journal

Year:

1998

Language:

english

File:

PDF, 175 KB

english, 1998

4

Bcl-2 family proteins: The sentinels of the mitochondrial apoptosis pathway

W. Wei-Lynn Wong, Hamsa Puthalakath

Journal:

Year:

2008

Language:

english

File:

PDF, 135 KB

english, 2008

5

Fatal Hepatitis Mediated by Tumor Necrosis Factor TNFα Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim

Thomas Kaufmann, Philipp J. Jost, Marc Pellegrini, Hamsa Puthalakath, Raffi Gugasyan, Steve Gerondakis, Erika Cretney, Mark J. Smyth, John Silke, Razq Hakem, Philippe Bouillet, Tak W. Mak, Vishva M. D

Journal:

Year:

2009

Language:

english

File:

PDF, 1.41 MB

english, 2009

6

The Role of Bim, a Proapoptotic BH3-Only Member of the Bcl-2 Family, in Cell-Death Control

ANDREAS STRASSER, HAMSA PUTHALAKATH, PHILIPPE BOUILLET, DAVID C.S. HUANG, LIAM O'CONNOR, LORRAINE A. O'REILLY, LEONIE CULLEN, SUZANNE CORY, JERRY M. ADAMS

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 60 KB

english, 2000

7

The Role of the Pro-Apoptotic Bcl-2 Family Member Bim in Physiological Cell Death

PHILIPPE BOUILLET, DAVID C.S. HUANG, LORRAINE A. O'REILLY, HAMSA PUTHALAKATH, LIAM O'CONNOR, SUZANNE CORY, JERRY M. ADAMS, ANDREAS STRASSER

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 53 KB

english, 2000

8

Cyclic-AMP-dependent protein kinase A regulates apoptosis by stabilizing the BH3-only protein Bim

Moujalled, Diane, Weston, Ross, Anderton, Holly, Ninnis, Robert, Goel, Pranay, Coley, Andrew, Huang, David CS, Wu, Li, Strasser, Andreas, Puthalakath, Hamsa

Journal:

Year:

2010

Language:

english

File:

PDF, 785 KB

english, 2010

9

corrigenda: BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

Bouillet, Philippe, Purton, Jared F., Godfrey, Dale I., Zhang, Li-Chen, Coultas, Leigh, Puthalakath, Hamsa, Pellegrini, Marc, Cory, Suzanne, Adams, Jerry M., Strasser, Andreas

Journal:

Year:

2002

Language:

english

File:

PDF, 59 KB

english, 2002

10

Egalitarian binds dynein light chain to establish oocyte polarity and maintain oocyte fate

Navarro, Caryn, Puthalakath, Hamsa, Adams, Jerry M., Strasser, Andreas, Lehmann, Ruth

Journal:

Nature Cell Biology

Year:

2004

Language:

english

File:

PDF, 1.68 MB

english, 2004

11

CD45 links the B cell receptor with cell survival and is required for the persistence of germinal centers

Huntington, Nicholas D, Xu, Yuekang, Puthalakath, Hamsa, Light, Amanda, Willis, Simon N, Strasser, Andreas, Tarlinton, David M

Journal:

Nature Immunology

Year:

2005

Language:

english

File:

PDF, 611 KB

english, 2005

12

Interleukin 15–mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1

Huntington, Nicholas D, Puthalakath, Hamsa, Gunn, Priscilla, Naik, Edwina, Michalak, Ewa M, Smyth, Mark J, Tabarias, Hyacinth, Degli-Esposti, Mariapia A, Dewson, Grant, Willis, Simon N

Journal:

Nature Immunology

Year:

2007

Language:

english

File:

PDF, 395 KB

english, 2007

13

Modifications and intracellular trafficking of FADD/MORT1 and caspase-8 after stimulation of T lymphocytes

O'Reilly, L A, Divisekera, U, Newton, K, Scalzo, K, Kataoka, T, Puthalakath, H, Ito, M, Huang, D C S, Strasser, A

Journal:

Cell Death & Differentiation

Year:

2004

Language:

english

File:

PDF, 597 KB

english, 2004

14

Proapoptotic Bcl-2 family member Bim is involved in the control of mast cell survival and is induced together with Bcl-XL upon IgE-receptor activation

Alfredsson, J, Puthalakath, H, Martin, H, Strasser, A, Nilsson, G

Journal:

Cell Death & Differentiation

Year:

2004

Language:

english

File:

PDF, 355 KB

english, 2004

15

Fold up or perish: unfolded protein response and chemotherapy

Strasser, A, Puthalakath, H

Journal:

Cell Death & Differentiation

Year:

2007

Language:

english

File:

PDF, 86 KB

english, 2007

16

What do we know about the mechanisms of elimination of autoreactive T and B cells and what challenges remain

Strasser, Andreas, Puthalakath, Hamsa, O'Reilly, Lorraine A, Bouillet, Philippe

Journal:

Immunology & Cell Biology

Year:

2007

Language:

english

File:

PDF, 302 KB

english, 2007

17

ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim

Hamsa Puthalakath, Lorraine A. O'Reilly, Priscilla Gunn, Lily Lee, Priscilla N. Kelly, Nicholas D. Huntington, Peter D. Hughes, Ewa M. Michalak, Jennifer McKimm-Breschkin, Noburo Motoyama, Tomomi Goto

Journal:

Year:

2007

Language:

english

File:

PDF, 1.41 MB

english, 2007

18

To Trigger Apoptosis, Bak Exposes Its BH3 Domain and Homodimerizes via BH3:Groove Interactions

Grant Dewson, Tobias Kratina, Huiyan W. Sim, Hamsa Puthalakath, Jerry M. Adams, Peter M. Colman, Ruth M. Kluck

Journal:

Year:

2008

Language:

english

File:

PDF, 2.01 MB

english, 2008

19

The Proapoptotic Activity of the Bcl-2 Family Member Bim Is Regulated by Interaction with the Dynein Motor Complex

Hamsa Puthalakath, David C.S Huang, Lorraine A O’Reilly, Stephen M King, Andreas Strasser

Journal:

Year:

1999

Language:

english

File:

PDF, 303 KB

english, 1999

20

CREB-binding protein (CBP) regulates β-adrenoceptor (β-AR)−mediated apoptosis

Lee, Y Y, Moujalled, D, Doerflinger, M, Gangoda, L, Weston, R, Rahimi, A, de Alboran, I, Herold, M, Bouillet, P, Xu, Q, Gao, X, Du, X-J, Puthalakath, H

Journal:

Cell Death & Differentiation

Year:

2013

Language:

english

File:

PDF, 3.33 MB

english, 2013

21

Role of p53 in cAMP/PKA pathway mediated apoptosis

Rahimi, Ahmad, Lee, Ying Ying, Abdella, Hassen, Doerflinger, Marcel, Gangoda, Lahiru, Srivastava, Rahul, Xiao, Kun, Ekert, Paul G., Puthalakath, Hamsa

Journal:

Year:

2013

Language:

english

File:

PDF, 443 KB

english, 2013

22

Hoxb8 regulates expression of microRNAs to control cell death and differentiation

Salmanidis, M, Brumatti, G, Narayan, N, Green, B D, van den Bergen, J A, Sandow, J J, Bert, A G, Silke, N, Sladic, R, Puthalakath, H, Rohrbeck, L, Okamoto, T, Bouillet, P, Herold, M J, Goodall, G J, J

Journal:

Cell Death & Differentiation

Year:

2013

Language:

english

File:

PDF, 929 KB

english, 2013

23

Endogenous bcl-2 is not required for the development of E -myc induced B-cell lymphoma

Kelly, P. N., Puthalakath, H., Adams, J. M., Strasser, A.

Journal:

Year:

2007

Language:

english

File:

PDF, 276 KB

english, 2007

24

Cloning and growth-regulated expression of the gene encoding the hepatitis B virus middle surface antigen in Yarrowia lipolytica

Hamsa, Puthalakath V., Chattoo, Bharat B.

Journal:

Year:

1994

Language:

english

File:

PDF, 851 KB

english, 1994

25

Loss of Prkar1a leads to Bcl-2 family protein induction and cachexia in mice

Gangoda, L, Doerflinger, M, Srivastava, R, Narayan, N, Edgington, L E, Orian, J, Hawkins, C, O'Reilly, L A, Gu, H, Bogyo, M, Ekert, P, Strasser, A, Puthalakath, H

Journal:

Cell Death & Differentiation

Year:

2014

Language:

english

File:

PDF, 3.56 MB

english, 2014

26

Bmf: A Proapoptotic BH3-Only Protein Regulated by Interaction with the Myosin V Actin Motor Complex, Activated by Anoikis

Puthalakath, H.

Journal:

Year:

2001

Language:

english

File:

PDF, 540 KB

english, 2001

27

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation

Lee, E. F., Czabotar, P. E., van Delft, M. F., Michalak, E. M., Boyle, M. J., Willis, S. N., Puthalakath, H., Bouillet, P., Colman, P. M., Huang, D. C.S., Fairlie, W. D.

Journal:

The Journal of Cell Biology

Year:

2008

Language:

english

File:

PDF, 2.97 MB

english, 2008

28

Evidence against upstream regulation of the unfolded protein response (UPR) by pro-apoptotic BIM and PUMA

Herold, M J, O'Reilly, L A, Lin, A, Srivastava, R, Doerflinger, M, Bouillet, P, Strasser, A, Puthalakath, H

Journal:

Cell Death and Disease

Year:

2014

Language:

english

File:

PDF, 621 KB

english, 2014

29

Cre transgene results in global attenuation of the cAMP/PKA pathway

Gangoda, L, Doerflinger, M, Lee, Y Y, Rahimi, A, Etemadi, N, Chau, D, Milla, L, O'Connor, L, Puthalakath, H

Journal:

Cell Death and Disease

Year:

2012

Language:

english

File:

PDF, 404 KB

english, 2012

30

Loss of the Pro-Apoptotic BH3-only Bcl-2 Family Member Bim Inhibits BCR Stimulation-induced Apoptosis and Deletion of Autoreactive B Cells

Enders, A., Bouillet, P., Puthalakath, H., Xu, Y., Tarlinton, D. M., Strasser, A.

Journal:

Journal of Experimental Medicine

Year:

2003

Language:

english

File:

PDF, 267 KB

english, 2003

31

Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic

Kuroda, J., Puthalakath, H., Cragg, M. S., Kelly, P. N., Bouillet, P., Huang, D. C. S., Kimura, S., Ottmann, O. G., Druker, B. J., Villunger, A., Roberts, A. W., Strasser, A.

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 1.38 MB

english, 2006

32

Glycosylation Defect in Lec1 Chinese Hamster Ovary Mutant Is Due to a Point Mutation in N-Acetylglucosaminyltransferase I Gene

Puthalakath, H., Burke, J., Gleeson, P. A.

Journal:

Journal of Biological Chemistry

Year:

1996

Language:

english

File:

PDF, 729 KB

english, 1996

33

MEK/ERK-Mediated Phosphorylation of Bim Is Required to Ensure Survival of T and B Lymphocytes during Mitogenic Stimulation

O'Reilly, L. A., Kruse, E. A., Puthalakath, H., Kelly, P. N., Kaufmann, T., Huang, D. C. S., Strasser, A.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 2.15 MB

english, 2009

34

Ubiquitylation and Cancer Development

Silke, John, Miasari, Maria, Puthalakath, Hamsa

Journal:

Current Cancer Drug Targets

Year:

2008

Language:

english

File:

PDF, 185 KB

english, 2008

35

Gefitinib-Induced Killing of NSCLC Cell Lines Expressing Mutant EGFR Requires BIM and Can Be Enhanced by BH3 Mimetics

Cragg, Mark S., Kuroda, Junya, Puthalakath, Hamsa, Huang, David C. S., Strasser, Andreas

Journal:

Year:

2007

Language:

english

File:

PDF, 419 KB

english, 2007

36

BH3-only proteins: a 20-year stock-take

Doerflinger, Marcel, Glab, Jason A., Puthalakath, Hamsa

Journal:

Year:

2015

Language:

english

File:

PDF, 647 KB

english, 2015

37

Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim

B. Marshall, H. Puthalakath, S. Caria, S. Chugh, M. Doerflinger, P. M. Colman, M. Kvansakul

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

38

A Novel BH3 Ligand That Selectively Targets Mcl-1 Reveals That Apoptosis Can Proceed without Mcl-1 Degradation

Erinna F. Lee, Peter E. Czabotar, Mark F. van Delft, Ewa M. Michalak, Michelle J. Boyle, Simon N. Willis, Hamsa Puthalakath, Philippe Bouillet, Peter M. Colman, David C. S. Huang and W. Douglas Fairli

Journal:

The Journal of Cell Biology

Year:

2008

Language:

english

File:

PDF, 2.52 MB

english, 2008

39

The PKA paradox: Is Bim the answer?

Coley, Andrew M., Moujalled, Diane, Puthalakath, Hamsa

Journal:

Year:

2011

File:

PDF, 620 KB

2011

40

The PKA paradox: Is Bim the answer?

Coley, Andrew M., Moujalled, Diane, Puthalakath, Hamsa

Journal:

Year:

2011

Language:

english

File:

PDF, 620 KB

english, 2011

41

[Methods in Molecular Biology] Programmed Cell Death Volume 1419 || Using CRISPR/Cas9 Technology for Manipulating Cell Death Regulators

Puthalakath, Hamsa, Hawkins, Christine J.

Year:

2016

Language:

english

File:

PDF, 479 KB

english, 2016

42

[Methods in Molecular Biology] Programmed Cell Death Volume 1419 || Detection of Cell Death in Drosophila Tissues

Puthalakath, Hamsa, Hawkins, Christine J.

Year:

2016

Language:

english

File:

PDF, 544 KB

english, 2016

43

[Methods in Molecular Biology] Programmed Cell Death Volume 1419 || Isolation of Cardiomyocytes and Cardiofibroblasts for Ex Vivo Analysis

Puthalakath, Hamsa, Hawkins, Christine J.

Year:

2016

Language:

english

File:

PDF, 475 KB

english, 2016

44

[Methods in Molecular Biology] Programmed Cell Death Volume 1419 || Hydrodynamic Injection as a Method of Gene Delivery in Mice: A Model of Chronic Hepatitis B Virus Infection

Puthalakath, Hamsa, Hawkins, Christine J.

Year:

2016

Language:

english

File:

PDF, 218 KB

english, 2016

45

[Methods in Molecular Biology] Programmed Cell Death Volume 1419 || Screening Strategies for TALEN-Mediated Gene Disruption

Puthalakath, Hamsa, Hawkins, Christine J.

Year:

2016

Language:

english

File:

PDF, 918 KB

english, 2016

46

[Methods in Molecular Biology] Programmed Cell Death Volume 1419 || Characterizing Bcl-2 Family Protein Conformation and Oligomerization Using Cross-Linking and Antibody Gel-Shift in Conjunction with Native PAGE

Puthalakath, Hamsa, Hawkins, Christine J.

Year:

2016

Language:

english

File:

PDF, 425 KB

english, 2016

47

[Methods in Molecular Biology] Programmed Cell Death Volume 1419 || Lentiviral Vectors to Analyze Cell Death Regulators

Puthalakath, Hamsa, Hawkins, Christine J.

Year:

2016

Language:

english

File:

PDF, 313 KB

english, 2016

48

[Methods in Molecular Biology] Programmed Cell Death Volume 1419 || Detection of Apoptotic Versus Autophagic Cell Death by Flow Cytometry

Puthalakath, Hamsa, Hawkins, Christine J.

Year:

2016

Language:

english

File:

PDF, 404 KB

english, 2016

49

[Methods in Molecular Biology] Programmed Cell Death Volume 1419 || In Vitro Differentiation of Mouse Granulocytes

Puthalakath, Hamsa, Hawkins, Christine J.

Year:

2016

Language:

english

File:

PDF, 426 KB

english, 2016

50

[Methods in Molecular Biology] Programmed Cell Death Volume 1419 || In Vivo Apoptosis Imaging Using Site-Specifically 68Ga-Labeled Annexin V

Puthalakath, Hamsa, Hawkins, Christine J.

Year:

2016

Language:

english

File:

PDF, 451 KB

english, 2016